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Synthetic Communications
An International Journal for Rapid Communication of Synthetic Organic Chemistry
Volume 40, 2010 - Issue 3
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Original Articles

Facile and Simple Synthesis of Novel 1-Methyl-2-(2-substituted-oxazol-4-yl)-1H-benzimidazole Derivatives

, , , &
Pages 414-422 | Received 23 Jan 2009, Published online: 06 Jan 2010
 

Abstract

Novel 1-methyl-2-(2-substituted-oxazol-4-yl)-1H-benzimidazole derivatives were obtained in good yields and purity by treating corresponding 2-benzimidazolyl esters with acetamide in the presence of BF3-etherate, a Lewis acid.

ACKNOWLEDGMENTS

The authors thank Dr. Reddy's Laboratories Ltd. for supporting this work. The authors also thank Mr. Abhijit Mukherjee and Dr. Vilas Dahanukar for their constant help and encouragement. The cooperation extended by all colleagues of the analytical division is gratefully acknowledged.

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