New Schiff's Base and 2-Azetidinone Derivatives of 3-Benzo[4,5]imidazo[2,1-b]thiazol-3-yl-chromen-2-one by Vilsmeier–Haack Formylation

Abstract

A new Schiff's base and 2-azetidinone derivatives obtained via the corresponding 3-benzo [4,5] imidazo [2,1-b] thiazol-3-yl-chromen-2-one by Vilsmeier–Haack formylation scaffold is described. Our design is aimed at obtaining new triheterocyclic and tetraheterocyclic derivatives.

Keywords:

• Antitumor agents
• azetidin-2-one
• DNA
• fused ring systems
• Schiff's base
• Vilsmeier–Haack formylation

ACKNOWLEDGMENTS

This research work is financially supported by the University Grant Commission (UGC), New Delhi [Ref. No. 33–296/2007 (SR)]. Dr. K. M. Hosamani is indebted to the British Commonwealth Scholarship Commission, UK [Ref. No. INCF-2008–68].