Oxidative Aromatization of Hantzsch 1,4-Dihydropyridines by H₂O₂/V₂O₅ at Room Temperature

Jinlong Su College of Chemistry and Chemical Engineering, Southwest University, Chongqing, China

Cai Zhang College of Chemistry and Chemical Engineering, Southwest University, Chongqing, China

Dan Lin College of Chemistry and Chemical Engineering, Southwest University, Chongqing, China

Yiqin Duan College of Chemistry and Chemical Engineering, Southwest University, Chongqing, China

Xiangkai Fu College of Chemistry and Chemical Engineering, Southwest University, Chongqing, China

Ruizhu Mu College of Chemistry and Chemical Engineering, Southwest University, Chongqing, ChinaCorrespondence[email protected]

Abstract

A mild and highly efficient synthetic method was developed for the aromatization of 1,4-dihydropyridines employing H₂O₂ and 5 mol% of V₂O₅. The reactions were carried out in CH₃CN to give pyridine compounds in excellent yields.

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ACKNOWLEDGMENT

The authors are grateful to Southwest University of China for financial support.

Notes

^aAll reactions were carried out at room temperature in CH₃CN.

^bIsolated yields.

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Oxidative Aromatization of Hantzsch 1,4-Dihydropyridines by H₂O₂/V₂O₅ at Room Temperature

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Oxidative Aromatization of Hantzsch 1,4-Dihydropyridines by H2O2/V2O5 at Room Temperature

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Oxidative Aromatization of Hantzsch 1,4-Dihydropyridines by H₂O₂/V₂O₅ at Room Temperature