General and Efficient Synthesis of O-Sulfonylhydroxylamine Derivatives

Abstract

A general and efficient synthetic route to O-sulfonylhydroxylamine derivatives is described. The approach involves acylation of hydroxylamine with benzyl chloroformate to give N-carbobenzoxy hydroxylamine, followed by sulfonation and hydrogenolysis to give products.

Keywords:

• Benzyl chloroformate
• hydrogenolysis
• O-sulfonylhydroxylamine derivatives
• sulfonation