Efficient Reducing System Based on Iron for Conversion of Nitroarenes to Anilines

Abstract

Reduction of nitroarenes with low solubility in EtOH–H₂O to anilines easily occurs in a Fe–NH₄Cl–acetone–H₂O system, and treatment of the same nitroarenes with Fe–NH₄Cl–EtOH–H₂O hardly furnished the corresponding products. Under the reaction condition, the reducible or hydrolysable groups are not affected.

Keywords:

• Aniline
• Fe–NH₄Cl–acetone–H₂O
• nitroarene
• reduction

ACKNOWLEDGMENT

The work was financed by Grant No. JSDXKYZZ0801 from Jishou University for talent introduction, Hunan Province, China, and by a project (JSU-CX-2009-42) of College Students' Research-Type Learning and Innovative Experiment from Jishou University, Hunan, China.