Approach to the Valorization of Carbohydrates as Raw Materials by Microwave-Assisted Neat 1,3-Dipolar Cycloaddition

Abstract

By reaction of C,N-diphenylnitrone and carbohydrates with a crotonyl side chain at their primary or anomeric carbon position, we explore the application of sugar derivatives as raw materials and chiral inducers in microwave-assisted neat 1,3-dipolar cycloadditions.

Keywords:

• Carbohydrate
• chiral auxiliary
• 1,3-dipolar cycloaddition
• microwave
• neat reaction