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Synthetic Communications
An International Journal for Rapid Communication of Synthetic Organic Chemistry
Volume 40, 2010 - Issue 11
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Original Articles

Efficient Syntheses of (±)-Cherylline and Latifine Dimethyl Ether

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Pages 1588-1594 | Received 18 Feb 2009, Published online: 06 May 2010
 

Abstract

A concise route for the syntheses of (±)-cherylline and latifine dimethyl ether is reported. The key steps involved are Michael addition of veratrole with p-methoxy nitrostyrene (for cherylline), anisole with 2,3-dimethoxy nitrostyrene (for latifine), and reduction of nitro intermediate, followed by Pictet–Spengler cyclization.

ACKNOWLEDGMENTS

We are grateful to SVNIT, Surat, and the Indian Institute of Chemical Technology, Hyderabad, for supporting this work.

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