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Synthetic Communications
An International Journal for Rapid Communication of Synthetic Organic Chemistry
Volume 40, 2010 - Issue 13
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Original Articles

Synthesis, Characterization, and Antimicrobial Studies of Bissydnones Based on 4,4′-Diaminodiphenyl Methane

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Pages 1899-1906 | Received 28 Mar 2009, Published online: 08 Jun 2010
 

Abstract

The aim of this investigation is to present the synthesis and characterization of some 3,3′-(methylenedi-1,4-phenylene)bis(4-substituted aminosulfonyl)sydnone (7a–j) and to evaluate their antimicrobial activity. All newly synthesized compounds were characterized by spectral data as well as by elemental analysis. Some compounds showed excellent activity against Gram-positive and Gram-negative bacteria.

ACKNOWLEDGMENT

The authors are thankful to Atul Limited, Valsad, for providing some useful chemicals.

Notes

Notes. IZ, inhibition of zone; MIC, minimum inhibitory concentration. Zone diameter of growth inhibition (mm) after 24 h.

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