Efficient and Mild Iron-Catalyzed Direct Allylation of Benzyl Alcohols and Benzyl Halides with Allyltrimethylsilane

Abstract

An efficient and mild iron-catalyzed direct allylation of benzyl alcohols and benzyl halides with allyltrimethylsilane has been developed. The present reaction would provide an excellent alternative to published methods because of its excellent yields, sustainable catalyst, and mild conditions.

Keywords:

• Allylation
• benzyl alcohols
• benzyl halides
• iron catalysis

ACKNOWLEDGMENT

We thank Gannan Normal University for financial support.

Notes

^a Reaction conditions: 1-phenyl-1-p-chlorophenyl methanol (0.5 mmol), allyltrimethylsilane (1.0 mmol), rt, 0.5 h.

^b Alcohol/allylsilane = 1:3.

^c Alcohol/allylsilane = 1:1.

^a Reaction conditions: benzyl alcohol or benzyl bromide (0.5 mmol), allyltrimethylsilane (1.0 mmol), 5 mol% FeCl₃·6H₂O (0.025 mmol), CH₂Cl₂, rt.