Ionic Liquid–Mediated, One-Pot Synthesis for 4-Thiazolidinones

Abstract

A convenient one-pot, three-component cyclocondensation mediated by ionic liquid for obtaining 2,3-disubstituted-4-thiazolidinones with excellent yields is reported.

Keywords:

• Mercaptoacetic acid
• N-methylpyridinium tosylate (ionic liquid)
• 4-thiazolidinones

ACKNOWLEDGMENT

The authors are thankful to Professor D. B. Ingle for his invaluable discussions and guidance.

Notes

^a Isolated yields.

^b The melting points of these products prepared in this work are in good agreement with those reported in the literature.^{[ 12 , 13 ]}