Synthesis, Crystal Structure, and Spectral Characterization of Flumatinib Mesylate

Gang Xu School of Chemistry and Chemical Engineering, Southeast University, Nanjing, China

Hong Shen School of Chemistry and Chemical Engineering, Nanjing University, Nanjing, China

Taifeng Tong School of Chemistry and Chemical Engineering, Southeast University, Nanjing, China

Aifeng Lu Jiangsu Haosen Pharmaceutical Corporation, Lianyungang, China

Shaohua Gou School of Chemistry and Chemical Engineering, Southeast University, Nanjing, ChinaCorrespondence[email protected]

Abstract

Flumatinib mesylate, a 3-substituted picolinamide derivative structurally similar to imatinib mesylate, was prepared. The compound was characterized by infrared, ultraviolet, NMR, and electrospray ionization–mass spectra together with x-ray crystal structure analysis.

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ACKNOWLEDGMENT

We thank Jiangsu Haosen Pharmaceutical Corporation very much for supporting this work.

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Synthesis, Crystal Structure, and Spectral Characterization of Flumatinib Mesylate

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Synthesis, Crystal Structure, and Spectral Characterization of Flumatinib Mesylate

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