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Synthetic Communications
An International Journal for Rapid Communication of Synthetic Organic Chemistry
Volume 40, 2010 - Issue 19
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Original Articles

Synthesis of Hydantoins, Thiohydantoins, and Glycocyamidines Under Solvent-Free Conditions

, , , &
Pages 2869-2874 | Received 06 Aug 2009, Published online: 25 Aug 2010
 

Abstract

Hydantoins, thiohydantoins, and glycocyamidines have been prepared in moderate to excellent yields at room temperature under solvent-free conditions. 3N-amino and carboamide derivatives of hydantoin (7–8) were prepared in single step by condensing benzil with semicarbazide and biuret respectively.

ACKNOWLEDGMENT

One of the authors is thankful to the Higher Education Commission of Pakistan for providing a fellowship.

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