Aqueous Synthesis of N-Phenyl/alkyl-2-quinolinone-3-carboxylic Acids from Coumarin-3-carboxylic Acids

Abstract

An efficient, ecofriendly aqueous synthesis of aromatic/aliphatic amines with coumarin-3-carboxylic acid in a one pot reaction in a sealed tube or InCl₃/ H₂O in open vessel to afford N-phenyl/alkyl-2-quinolinones is achieved. This method provides high yield of products in shorter time, making it a useful process for the synthesis of structurally diversified 2-quinolinones from corresponding coumarins.

Keywords:

• Coumarin-3-carboxylic acid
• N-phenyl/alkyl-2-quinolinones
• one pot

ACKNOWLEDGMENT

The authors thank the Department of Postgraduate Studies and Research in Chemistry, School of Chemical Sciences, Kuvempu University, for providing laboratory facilities.

Notes

^a Isolated yields.

^a Isolated yield.