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Synthetic Communications
An International Journal for Rapid Communication of Synthetic Organic Chemistry
Volume 40, 2010 - Issue 22
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Original Articles

Aqueous Synthesis of N-Phenyl/alkyl-2-quinolinone-3-carboxylic Acids from Coumarin-3-carboxylic Acids

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Pages 3281-3289 | Received 02 Aug 2009, Published online: 15 Oct 2010
 

Abstract

An efficient, ecofriendly aqueous synthesis of aromatic/aliphatic amines with coumarin-3-carboxylic acid in a one pot reaction in a sealed tube or InCl3/ H2O in open vessel to afford N-phenyl/alkyl-2-quinolinones is achieved. This method provides high yield of products in shorter time, making it a useful process for the synthesis of structurally diversified 2-quinolinones from corresponding coumarins.

ACKNOWLEDGMENT

The authors thank the Department of Postgraduate Studies and Research in Chemistry, School of Chemical Sciences, Kuvempu University, for providing laboratory facilities.

Notes

a Isolated yields.

a Isolated yield.

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