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Synthetic Communications
An International Journal for Rapid Communication of Synthetic Organic Chemistry
Volume 40, 2010 - Issue 22
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Original Articles

Practical Synthesis of FEt-penta-cyclofenil and Its Derivatives for Potential PET Imaging

, , &
Pages 3322-3331 | Received 01 Apr 2009, Published online: 15 Oct 2010
 

Abstract

Generally, FEt-penta-cyclofenil and its derivatives have greater relative binding affinity to estradiol receptors than estradiol. (4-Fluoroethoxyphenyl)–(4′-hydroxyphenyl) methylenecyclopentane and its derivatives were synthesized for potential radioactive image agents, and their structures were characterized by ultraviolet, infrared, 1H NMR, 19F NMR, and high-resolution mass spectrometry.

ACKNOWLEDGMENT

This project was supported by the Hundred Talent Program of the Chinese Academy of Sciences (No. 26200601).

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