A New Bismuth Nitrate–Catalyzed Electrophilic Substitution of Indoles with Carbonyl Compounds Under Solvent-Free Conditions

Laura Iglesias Department of Chemistry, The University of Texas–Pan American, Edinburg, Texas, USA

Calista Aguilar Department of Chemistry, The University of Texas–Pan American, Edinburg, Texas, USA

Debasish Bandyopadhyay Department of Chemistry, The University of Texas–Pan American, Edinburg, Texas, USA

Bimal K. Banik Department of Chemistry, The University of Texas–Pan American, Edinburg, Texas, USACorrespondence[email protected]

Abstract

An expeditious synthetic method for the preparation of bis(indollyl)methane derivatives has been developed through a bismuth nitrate-catalyzed reaction of indole with various carbonyl compounds in mortar and pastle under solvent-free conditions.

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ACKNOWLEDGMENT

We gratefully acknowledge the funding support from the NIH-SCORE (Grant # 2S06M008038-37).

Notes

L. I. and C. A. are undergraduate research participants.

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A New Bismuth Nitrate–Catalyzed Electrophilic Substitution of Indoles with Carbonyl Compounds Under Solvent-Free Conditions

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A New Bismuth Nitrate–Catalyzed Electrophilic Substitution of Indoles with Carbonyl Compounds Under Solvent-Free Conditions

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ACKNOWLEDGMENT

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