Advanced search
Publication Cover
Synthetic Communications
An International Journal for Rapid Communication of Synthetic Organic Chemistry
Volume 41, 2011 - Issue 3
Submit an article Journal homepage
580
Views
71
CrossRef citations to date
0
Altmetric
Original Articles

Rapid Synthesis of Polyfunctionalized Pyrano[2,3-c]pyrazoles via Multicomponent Condensation in Room-Temperature Ionic Liquids

Jitender M. Khurana Department of Chemistry, University of Delhi, Delhi, IndiaCorrespondence[email protected]
,
Bhaskara Nand Department of Chemistry, University of Delhi, Delhi, India
&
Sanjay Kumar Department of Chemistry, University of Delhi, Delhi, India
Pages 405-410 | Received 03 Oct 2009, Published online: 13 Jan 2011
 
Sample our Physical Sciences journals, sign in here to start your FREE access for 14 days

Abstract

A highly efficient synthesis of 4H-pyrano[2,3-c]pyrazoles has been completed using four-component cyclocondensation of hydrazine monohydrate/phenyl hydrazine, ethyl acetoacetate, aldehydes, and malononitrile in the presence of L-proline and room-temperature ionic liquids.

ACKNOWLEDGMENTS

Financial assistance by the Council of Scientific and Industrial Research, New Delhi, India, as a junior research fellowship to Bhaskara Nand and junior and senior research fellowships to Sanjay Kumar is gratefully acknowledged.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Order Reprints Request Corporate Permissions

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

Request Academic Permissions

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.

Related Research Data

Efficient and green synthesis of 4H-pyrans and 4H-pyrano[2,3-c] pyrazoles catalyzed by task-specific ionic liquid [bmim]OH under solvent-free conditions
Source: Informa UK Limited
Green chemistry: science and politics of change.
Source: American Association for the Advancement of Science (AAAS)
Three‐Component One‐Pot Synthesis of 1,4‐Dihydropyrano[2,3‐c]pyrazole Derivatives in Aqueous Media
Source: Informa UK Limited
An expedient four-component domino protocol for the synthesis of novel benzo[a]phenazine annulated heterocycles and their photophysical studies
Source: Royal Society of Chemistry (RSC)
D,L‐Proline‐Catalyzed One‐Pot Synthesis of Pyrans and Pyrano[2,3‐c]pyrazole Derivatives by a Grinding Method under Solvent‐Free Conditions
Source: Informa UK Limited
Mesoporous halloysite nanotubes modified by CuFe 2 O 4 spinel ferrite nanoparticles and study of its application as a novel and efficient heterogeneous catalyst in the synthesis of pyrazolopyridine derivatives.
Source: Springer Science and Business Media LLC
Zn(L-proline)2: a Catalyst for Multicomponent Reactions
Source: Wiley
Synthesis of 6-Amino-2,4-dihydropyrano[2,3-c]pyrazol-5-carbonitriles Catalyzed by Silica-Supported Tetramethylguanidine Under Solvent-Free Conditions
Source: Informa UK Limited
Comprehensive Kinetics and a Mechanistic Investigation on the Biological Active Pyrano[2,3-C]Pyrazole Core in the Presence of Both Eco-Friendly Catalyst and Solvent: Experimental Green Protocol
Source: Taylor & Francis
Ionic liquids catalyzed Biginelli reaction under solvent-free conditions
Source: Elsevier BV
A new route to substituted 3-methoxycarbonyldihydropyrans; enantioselective synthesis of (–)-methyl elenolate
Source: Royal Society of Chemistry (RSC)
Facile and Chemically Sustainable One‐Pot Synthesis of a Wide Array of Fused O‐ and N‐Heterocycles Catalyzed by Trisodium Citrate Dihydrate under Ambient Conditions
Source: Wiley
A Facile One Pot Synthesis of Pyrano[2,3‐c]pyrazole Derivatives under Microwave Irradiation.
Source: Wiley
One-pot multicomponent synthesis of highly functionalized bio-active pyrano[2,3-c]pyrazole and benzylpyrazolyl coumarin derivatives using ZrO2 nanoparticles as a reusable catalyst
Source: Royal Society of Chemistry (RSC)
Synthesis and Molluscicidal Activity of New Cinnoline and Pyrano[2,3‐c]pyrazole Derivatives.
Source: Wiley
Preparation and characterization of hexamethylenetetramine‐functionalized magnetic nanoparticles and their application as novel catalyst for the synthesis of pyranopyrazole derivatives
Source: Wiley
Three-Component Combinatorial Synthesis of Novel Dihydropyrano[2,3-c]pyrazoles
Source: American Chemical Society (ACS)
Multicomponent reactions in unconventional solvents: state of the art
Source: Royal Society of Chemistry (RSC)
New developments in catalysis using ionic liquids
Source: Elsevier BV
Recent developments in synthetic chemistry and biological activities of pyrazole derivatives
Source: Springer Science and Business Media LLC
Synthesis of Biologically Relevant Heterocycles in Aqueous Media
Source: Wiley
Aliphatic aldehydes in the synthesis of condensed 4-alkyl(cycloalkyl)-2-amino-3-cyano-4H-pyrans
Source: Springer Science and Business Media LLC
Choline chloride based thiourea catalyzed highly efficient, eco-friendly synthesis and anti-bacterial evaluation of some new 6-amino-4-aryl-2,4-dihydro-3-phenyl pyrano [2,3-c] pyrazole-5-carbonitrile derivatives
Source: Springer Science and Business Media LLC
6-Amino-5-cyano-1H,4H-pyrazolo[3,4-b]pyrans
Source: Springer Science and Business Media LLC
Desulfurization of thioureas, benzimidazoline-2-thiones and 1,3-dihydro-1,3-diaryl-2-thioxopyrimidine-4,6(2H,5H)-diones with nickel boride at ambient temperature
Source: Royal Society of Chemistry (RSC)
Multiple-Component Condensation Strategies for Combinatorial Library Synthesis
Source: American Chemical Society (ACS)
Four component synthesis of highly functionalized pyrano[2,3-c]pyrazoles from benzyl halides
Source: Informa UK Limited
Efficient Synthesis of 1,4-Dihydropyrano[2,3-c]pyrazoles Using Snail Shell as a Biodegradable and Reusable Catalyst
Source: Informa UK Limited
Ionic liquid-regulated sulfamic acid: chemoselective catalyst for the transesterification of β-ketoesters
Source: Elsevier BV
Synthetic Developments in Functionalized Pyrano[2,3-c]pyrazoles. A Review
Source: Informa UK Limited

Linking provided by 

Related research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.