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Synthetic Communications
An International Journal for Rapid Communication of Synthetic Organic Chemistry
Volume 41, 2011 - Issue 3
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Original Articles

Nanocrystalline Copper(II) Oxide–Catalyzed One-Pot Synthesis of Imidazo[1,2-a]quinoline and Quinolino[1,2-a]quinazoline Derivatives via a Three-Component Condensation

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Pages 426-435 | Received 01 Oct 2009, Published online: 13 Jan 2011
 

Abstract

A simple, efficient, and practical procedure for the synthesis of imidazo[1,2-a]quinoline and quinolino[1,2-a]quinazoline derivatives using CuO nanoparticles as a novel catalyst in excellent yields is described. The catalyst can be recovered conveniently and reused at least four times without any loss of activity.

ACKNOWLEDGMENT

The authors are thankful to the Nuclear Science and Technology Research Institute for the partial financial support.

Notes

a Reaction conditions: benzaldehyde (1 mmol), malononitrile (1 mmol), and enaminone 1a (1 mmol), x mmol% catalyst; water; 50 °C.

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