Abstract
The N-alkyl oxaziridines may be used as reagents for the oxidation of sulfides in acid-promoted reactions. The present work describes the behavior of two newly synthesized dihydroisoquinoline-derived oxaziridines with respect to methanesulfonic acid. An isomerization reaction was observed in the absence of sulfide.
Notes
a Reaction performed at room temperature in CH2Cl2.
b 0.5 mmol of sulfide (0,16 M), 2 equivalent of MsOH, and 1 equivalent of oxaziridine.
c Determined by TLC.
d Determined by 1H NMR spectroscopy in CDCl3.
e Isolated product.