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Synthetic Communications
An International Journal for Rapid Communication of Synthetic Organic Chemistry
Volume 41, 2011 - Issue 14
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Original Articles

(Bromodimethyl)sulfonium Bromide Mediated Rapid and Facile Protection of Amines

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Pages 2073-2080 | Received 14 Dec 2009, Published online: 20 May 2011
 

Abstract

A new clean protocol for protection of aryl and aliphatic amines with t-butoxycarbonyl (t-BOC) and benzyloxycarbonyl (Cbz) catalyzed by simple (bromodimethyl)sulfonium bromide has been developed. Rapid protection of amines in excellent yields in totally solvent-free conditions has been achieved.

Notes

Note: The superscript number in yield column is the reference number for reported compounds.

Note: The superscript number in yield column is the reference number for reported compounds.

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