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Novel spiro[1,4,2-dioxazole-5,3′-indolin]-2′-one derivatives were synthesized by 1,3-dipolar cycloaddition reactions of the isatin derivative with aryl nitrile oxide. The cycloadducts were characterized by spectral data including 1H NMR, 13C NMR, infrared, mass spectra, and elementary analysis.
The authors acknowledge the financial support provided by the Ministry ESRSFC of the Moroccan Government (Pôle de Compétences Pharmacochimie) and IUT Béthune.
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