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Synthetic Communications
An International Journal for Rapid Communication of Synthetic Organic Chemistry
Volume 41, 2011 - Issue 15
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Original Articles

Synthesis of Bis(phosphonatomethyl)-, Bis(phosphinatomethyl)-, and Bis(phosphinoxidomethyl)amines, as Well as Related Ring Bis(phosphine) Platinum Complexes

György Keglevich Department of Organic Chemistry and Technology, Budapest University of Technology and Economics, Budapest, HungaryCorrespondence[email protected]
,
Anna Szekrényi Department of Organic Chemistry and Technology, Budapest University of Technology and Economics, Budapest, Hungary
,
Áron Szöllősy Department of Inorganic and Analytical Chemistry, Budapest University of Technology and Economics, Budapest, Hungary
&
László Drahos Hungarian Academy of Sciences, Chemical Research Center, Budapest, Hungary
Pages 2265-2272 | Received 22 Apr 2010, Published online: 25 May 2011
 
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Abstract

The double Kabachnik–Fields condensation of primary amines with 2 equivalents of the other reagents (formaldehyde and a >P(O)H species, such as dialkyl phosphites, diphenylphosphine oxide, as well as the related dioxaphosphorine and oxaphosphorine derivatives) carried out under microwave conditions afforded the title products in 79–94% yields. The bis(phosphinoxidomethyl)amines were converted, after double deoxygenation, to the corresponding ring platinum complexes.

ACKNOWLEDGMENTS

G. K. is grateful to Professor Harry R. Hudson (London Metropolitan University) for his advice. This project was supported by the Hungarian Scientific and Research Fund (OTKA K83118).

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