Abstract
Palladium-catalyzed synthetic methodology has been developed for the synthesis of 2-aminobenzenesulfonic acids from benzothiazoles in good to excellent yields using chloramine-B in alkaline (pH 12) acetonitrile/water (1:1) at 80 °C.
Notes
a Substrate: 1 mmol, Chloramine-B = 5 mmol, temperature = 80 °C, time = 24–26 h.
b Mps given in parentheses refer to authentic samples.