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Synthetic Communications
An International Journal for Rapid Communication of Synthetic Organic Chemistry
Volume 41, 2011 - Issue 16
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Original Articles

Synthesis of N-Boc-C1 Vinyl Tetrahydroisoquinoline via Zn-Mediated Intramolecular Cyclization of N-Boc Protected Iodo Acetonide

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Pages 2385-2391 | Received 19 Mar 2010, Published online: 14 Jun 2011
 

Abstract

The Zn-mediated elimination of N-Boc protected iodo acetonide undergoes intramolecular cyclization to afford N-Boc-C1 vinyl tetrahydroisoquinoline in good yield.

ACKNOWLEDGMENTS

R. T. S. is thankful to the Council for Scientific and Industrial Research, New Delhi, for a senior research fellowship. We are grateful to the Department of Science and Technology, New Delhi, and Board of College and University Development (BCUD) and Shimadzu Analytical Centre, University of Pune, for financial assistance and spectral analysis, respectively.

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