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The reaction of ethyl 5-oxo-2,5-dihydroisoxzole-4-carboxylate with derivatives of 2-chloroquinoline afforded the desired N-quinolinyl isoxazolones. Their reactions with triethylamine in chloroform produced the corresponding pyrimidoquinoline derivatives, through intramolecular cyclization.
The authors are grateful for support of this work from the University of Urmia.
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