Simple and Efficient One-Pot Synthesis of Nitriles from Amides and Oximes Using in Situ–Generated Burgess-Type Reagent

John P. Rappai Department of Applied Chemistry, Cochin University of Science and Technology, Cochin, Kerala, India; Department of Chemistry, Government Victoria College, Palakkad, Kerala, India

Jayakumar Karthikeyan Department of Applied Chemistry, Cochin University of Science and Technology, Cochin, Kerala, India

Sreedharan Prathapan Department of Applied Chemistry, Cochin University of Science and Technology, Cochin, Kerala, India

Perupparampil A. Unnikrishnan Department of Applied Chemistry, Cochin University of Science and Technology, Cochin, Kerala, IndiaCorrespondence[email protected]

Abstract

The dehydration of aldoximes and amides, and oxidation of benzoin are accomplished in one-pot using in situ–generated Burgess-type reagent.

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ACKNOWLEDGMENT

This work was supported by the Council of Scientific and Industrial Research, Government of India, in the form of Research Grant No. 01(1989)/05/EMR-II.

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Simple and Efficient One-Pot Synthesis of Nitriles from Amides and Oximes Using in Situ–Generated Burgess-Type Reagent

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Simple and Efficient One-Pot Synthesis of Nitriles from Amides and Oximes Using in Situ–Generated Burgess-Type Reagent

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