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Synthetic Communications
An International Journal for Rapid Communication of Synthetic Organic Chemistry
Volume 41, 2011 - Issue 22
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Original Articles

KAl(SO4)2 · 12H2O as a Recyclable Lewis Acid Catalyst for Synthesis of Spirooxindoles in Aqueous Media

, , &
Pages 3344-3350 | Received 09 Jun 2010, Published online: 26 Jul 2011
 

Abstract

A simple and efficient procedure for the synthesis of spirooxindole has been described that employs a three-component condensation reaction in one pot using isatin, active methylene reagent, and 1,3-dicarbonyl compounds in an aqueous medium.

ACKNOWLEDGMENTS

We are grateful to Alzahra University Research Council for partial support of this work.

Notes

a Isolated yields.

a Isolated yields.

a Isolated yields.

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