Abstract
5-(Alkylimino)-2-(diethoxyphosphoryl)-2,5-dihydrofuran-3,4-dicarboxylates are prepared via a one-pot, three-component reaction of α-ketophosphonates, isocyanides, and dialkyl acetylenedicarboxylates at room temperature and neutral conditions. The structures of the products were deduced from their 1H NMR, 13C NMR, and infrared spectra and mass spectrometry.