Publication Cover
Synthetic Communications
An International Journal for Rapid Communication of Synthetic Organic Chemistry
Volume 41, 2011 - Issue 24
279
Views
2
CrossRef citations to date
0
Altmetric
Original Articles

One-Pot, Stereoselective Synthesis of Trisubstituted 1,3-Dienes by Hydromagnesiation–Cross-Coupling Tandem Reaction of Alkylarylacetylenes with Alkenyl Iodides

, , &
Pages 3728-3734 | Received 30 Jan 2010, Published online: 22 Aug 2011
 

Abstract

Trisubstituted 1,3-dienes can be stereoselectively synthesized in one pot under mild conditions, in good yields, by hydromagnesiation of alkylarylacetylenes, followed by the palladium-catalyzed cross-coupling with alkenyl iodides.

ACKNOWLEDGMENTS

We thank the National Natural Science Foundation of China (Project No. 20862008) and the Natural Science Foundation of Jiangxi Province in China (Project No. 2007GZW0172) for financial support.

Notes

a Isolated yield based on alkenyl iodide 3.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.