Abstract
Trisubstituted 1,3-dienes can be stereoselectively synthesized in one pot under mild conditions, in good yields, by hydromagnesiation of alkylarylacetylenes, followed by the palladium-catalyzed cross-coupling with alkenyl iodides.
ACKNOWLEDGMENTS
We thank the National Natural Science Foundation of China (Project No. 20862008) and the Natural Science Foundation of Jiangxi Province in China (Project No. 2007GZW0172) for financial support.
Notes
a Isolated yield based on alkenyl iodide 3.