PEG-Mediated Catalyst-Free Synthesis of Hantzsch 1,4-Dihydropyridines and Polyhydroquinoline Derivatives

V. Siddaiah Department of Organic Chemistry, Food, Drugs and Water, Andhra University, Visakhapatnam, IndiaCorrespondence[email protected]

G. Mahaboob Basha Department of Organic Chemistry, Food, Drugs and Water, Andhra University, Visakhapatnam, India

G. Padma Rao Department of Organic Chemistry, Food, Drugs and Water, Andhra University, Visakhapatnam, India

U. Viplava Prasad Department of Organic Chemistry, Food, Drugs and Water, Andhra University, Visakhapatnam, India

R. Suryachendra Rao Department of Chemistry, Acharya Nagarjuna University, Guntur, India

Abstract

Hantzsch 1,4-dihydropyridines and polyhydroquinoline derivatives were synthesized in good yields by PEG-mediated, catalyst–free synthesis under solvent-free conditions. The products were directly recrystallized from hot methanol. The reaction gave excellent yields with low- as well as high-molecular-weight polyethylene glycols.

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ACKNOWLEDGMENT

We gratefully acknowledge the financial support from the Department of Science and Technology (DST), New Delhi.

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PEG-Mediated Catalyst-Free Synthesis of Hantzsch 1,4-Dihydropyridines and Polyhydroquinoline Derivatives

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PEG-Mediated Catalyst-Free Synthesis of Hantzsch 1,4-Dihydropyridines and Polyhydroquinoline Derivatives

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GRAPHICAL ABSTRACT

ACKNOWLEDGMENT

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