Reaction of 2-Naphthylamine with Sodium Iodate/Sodium Sulfite: Synthesis of 2-Amino-1-iodonaphthalene

Tony Taldone Program in Molecular Pharmacology and Chemistry and Department of Medicine, Memorial Sloan-Kettering Cancer Center, New York, New York, USA

Danuta Zatorska Program in Molecular Pharmacology and Chemistry and Department of Medicine, Memorial Sloan-Kettering Cancer Center, New York, New York, USA

Gabriela Chiosis Program in Molecular Pharmacology and Chemistry and Department of Medicine, Memorial Sloan-Kettering Cancer Center, New York, New York, USACorrespondence[email protected]

Abstract

The reaction of 2-naphthylamine with NaIO₃/Na₂SO₃/HCl yields exclusively 2-amino-1-iodonaphthalene and not regioisomer 2-amino-3-iodonaphthalene as was previously reported. The assigned structure is supported by spectroscopic data.

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Reaction of 2-Naphthylamine with Sodium Iodate/Sodium Sulfite: Synthesis of 2-Amino-1-iodonaphthalene

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Reaction of 2-Naphthylamine with Sodium Iodate/Sodium Sulfite: Synthesis of 2-Amino-1-iodonaphthalene

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