Abstract
An efficient and environmentally benign process for the synthesis of quinoxalines has been developed using glycerine–cerium chloride as a reaction medium. This method is applicable to a variety of diketones and 1,2-phenylenediamines to afford the corresponding quinoxaline derivatives in excellent yields. The reaction medium was recovered and reused for further reactions without any problem.
GRAPHICAL ABSTRACT
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ACKNOWLEDGMENT
J. K. K. is thankful to the University Grants Commission, New Delhi, for providing a fellowship.
Notes
a All the products were identified by their 1H NMR, IR, and mass.
b Yields were isolated and not optimized.