Abstract
A facile, one-pot, three-component bis heterocyclized reaction for the synthesis of hydrazonothiazolyl-pyrazolones has been described. Reaction of phenacyl bromides or 3-(2-bromoacetyl)coumarins, with thiosemicarbazide and ethyl 2-(2-arylhydrazono)-3-oxobutanoates in AcOH/NaOAc, gave the corresponding products in good yields. All the synthesized compounds were characterized by their analytical and spectral data.
GRAPHICAL ABSTRACT
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ACKNOWLEDGMENTS
The authors are thankful to the director, NIT, Warangal, for providing facilities. One of the authors (C. H. V. S. R.) is thankful to the director for an institute fellowship.