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Abstract
In a wide search program for new and efficient antimicrobial agents, a series of oxadiazole/azetidinone-incorporated benzimidazoles have been synthesized and evaluated against different Gram-positive and Gram-negative bacteria. Derivatives having long alkyl chain on the oxadiazole/azetidinone moiety with three or more carbon atoms have shown less antibacterial activity.
GRAPHICAL ABSTRACT
ACKNOWLEDGMENT
Authors are thankful to the University Grants Commission, New Delhi, India, for providing financial grant vide F. No. 37-494/2009 (SR).
Notes
Notes: Total inhibition (no growth of organism), –; poor growth compared to control, P; medium growth compared to control, +; and confluent growth (no inhibition), + +.
Notes: Total inhibition (no growth of organism), –; poor growth compared to control, P; medium growth compared to control, +; and confluent growth (no inhibition), + +.
Notes: Total inhibition (no growth of organism), –; poor growth compared to control, P; medium growth compared to control, +; and confluent growth (no inhibition), ++.