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Synthetic Communications
An International Journal for Rapid Communication of Synthetic Organic Chemistry
Volume 43, 2013 - Issue 3
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Original Articles

Efficient Synthesis of Benzodiazepino and Pyrazino Carbazoles

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Pages 375-383 | Received 25 Apr 2011, Published online: 02 Nov 2012
 

Abstract

An efficient method for the synthesis of benzodiazepino and pyrazino-annelated carbazoles by the facile reaction of 2,3,4,9-tetrahydro-1H–carbazol-1-one with anthranilic acid, 3-aminopyrazine-2-carboxylic acid, and glycine catalyzed by polyphosphoric acid has been carried out.

Supplementary meterials are available for this article. Go to the publisher's online edition of Synthetic Communications® to view the free supplemental file.

GRAPHICAL ABSTRACT

ACKNOWLEDGMENTS

The authors thank the Indian Institute of Science, Bangalore, Indian Institute of Technology Madras, Chennai, for NMR and Indian Institute of Chemical Technology, Hyderabad, for mass spectral data.

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