Efficient Synthesis of Pyrrolo[1,2-f]phenanthridine Derivatives via Dipolar Cycloaddition of Phenanthridine, Activated Acetylenes, and Ethyl Bromopyruvate

Abstract

The three-component reactions of phenanthridine, activated acetylenes, and ethyl bromopyruvate through both of simultaneous and stepwise process are surveyed. The reactions afforded the corresponding pyrrolo[1,2-f]phenanthridine derivatives in good yields without using any catalyst and activation.

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GRAPHICAL ABSTRACT

Keywords:

• Ethyl bromopyruvate
• phenanthridine
• pyrrolo[1,2-f]phenanthridines
• three-component reactions