CuFe₂O₄ Nanoparticles: A Magnetically Recoverable and Reusable Catalyst for the Synthesis of Coumarins via Pechmann Reaction in Water

Abstract

The synthesis of coumarins by hydroxyalkylation of phenols with ethyl acetoacetate (via Pechmann reaction) is attempted using magnetically separable and reusable CuFe₂O₄ nanoparticles in water.

[Supplementary materials are available for this article. Go to the publisher's online edition of Synthetic Communications ^® for the following free supplemental resource(s): Full experimental and spectral details.]

GRAPHICAL ABSTRACT

Keywords:

• Coumarins
• CuFe₂O₄ nanoparticles
• heterogeneous catalyst
• Pechmann reaction

ACKNOWLEDGMENT

This research is supported by the Islamic Azad University, Ayatollah Amoli Branch.

Notes

^a Reaction conditions: resorcinol (1 mmol) and ethyl acetoacetate (1.2 mmol).

^b Isolated yield.

^a Isolated yields of pure products.

^a Reaction condition: resorcinol (1 mmol), ethyl acetoacetate (1.2 mmol), CuFe₂O₄ nanoparticles as a catalyst 5 mol% in water.

^b Isolated yield.