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Synthetic Communications
An International Journal for Rapid Communication of Synthetic Organic Chemistry
Volume 44, 2014 - Issue 9
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Original Articles

Room-Temperature Synthesis of Hydroxylnaphthalene-1,4-dione Derivative Catalyzed by Phenylphosphinic Acid

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Pages 1286-1290 | Received 18 Jul 2013, Published online: 28 Mar 2014
 

Abstract

An efficient one-pot synthesis of hydroxylnaphthalene-1,4-dione derivatives is accomplished by a three-component reaction of 2-hydroxynaphthalene-1,4-dione, aromatic aldehydes, and amines in water under ambient temperature catalyzed by phenylphosphinic acid. This method has the advantages of good yield, mild reaction conditions, simple workup, environmental friendliness and cost efficiency.

GRAPHICAL ABSTRACT

Notes

a Isolated yield.

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