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Synthetic Communications
An International Journal for Rapid Communication of Synthetic Organic Chemistry
Volume 44, 2014 - Issue 15
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Original Articles

New Synthesis of (±)-Cherylline and Mono- and Dimethyl Ethers

, &
Pages 2232-2238 | Received 28 Dec 2013, Published online: 06 Jun 2014
 

Abstract

The synthesis of 4-aryl-1,2,3,4-tetrahydroisoquinolines is achieved via the ether rearrangement methodology. Subsequent reactions yielded cherylline and ether derivatives of amaryllidaceac alkaloids.

GRAPHICAL ABSTRACT

ACKNOWLEDGMENT

We thank Suven Life Sciences for the excellent analytical facilities and allowing us to publish these results.

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