PEG₁₀₀₀-Based Dicationic Acidic Ionic Liquid as an Efficient Catalyst for Mannich-Type Reaction in Water

Abstract

PEG₁₀₀₀-based dicationic acidic ionic liquid (PEG₁₀₀₀-DAIL) was found to be an efficient and recyclable catalyst for Mannich-type reaction of different ketones with various aromatic aldehydes and aromatic amines in water to give various β-arylamino ketones in good yields. The catalytic system could be easily recovered and reused for at least six runs only with slight decrease in its activity.

GRAPHICAL ABSTRACT

Keywords:

• β-Arylamino ketones
• ionic liquid
• Mannich reaction
• multicomponent reactions
• poly(ethylene glycol)

Notes

^a Isolated yields.

^b The system of H₂O/ PEG₁₀₀₀-DAIL was run for six consecutive cycles.

^a Isolated yields.