Ceric Ammonium Nitrate (CAN)–Catalyzed, Efficient, One-Pot, Three-Component, aza-Diels–Alder Reactions for a Facile Synthesis of Tetrahydropyranoquinoline Derivatives

Abstract

A simple, efficient, and cost-effective method for the synthesis of tetrahydropyranoquinoline derivatives by a one-pot condensation of aromatic aldehyde, aromatic amine, and 3,4-dihydro-2H-pyran respectively in the presence of ceric ammonium nitrate (CAN) has been described.

GRAPHICAL ABSTRACT

Keywords:

• 3,4-Dihydro-2H-pyran
• multicomponent reactions
• tetrahydropyranoquinolines

ACKNOWLEDGMENTS

The author’s gratefully acknowledge the Director of CSIR-IICT, Hydrabad, and the Head, Organic and Biomolecular Chemistry Division, CSIR-IICT, for their constant encouragement and support.

SUPPLEMENTAL MATERIAL

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