Design and Synthesis of Pyrano[2,3-a]carbazoles by Multicomponent Reaction

Abstract

A facile, efficient, three-component reaction of 2,3,4,9-tetrahydro-1H-carbazol-1-one, malononitrile, and aromatic/heteroaromatic aldehydes in dimethylformamide (DMF) gave pyrano[2,3-a]carbazoles in good yields, at reflux condition, using a catalytic amount of piperidine.

GRAPHICAL ABSTRACT

Keywords:

• Aldehydes
• malononitrile
• multicomponent reaction
• piperidine
• pyrano[2,3-a]carbazoles

ACKNOWLEDGMENTS

The authors thank the Indian Institute of Science, Bangalore, for NMR data and the Indian Institute of Chemical Technology, Hyderabad, for mass spectral data.

SUPPLEMENTAL MATERIAL

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