Abstract
The synthesis of quinoxalines via a tandem oxidation process using a copper acetate monohydrate/2,2,6,6-tetramethylpiperidine N-oxyl (TEMPO) oxidative system has been described. Using this approach, a series of quinoxaline derivatives were formed in good yields within short reaction times under microwave irradiation. The oxidative system was also extended to the selective synthesis of dihydropyrazines and pyrazines.
GRAPHICAL ABSTRACT
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