Abstract
A simple and efficient method for the construction of quinoline derivatives from 2-azidobenzaldehyde and various carbonyl compounds was developed. The process involves a Knoevenagel condensation of 2-azidobenzaldehyde with carbonyl compound and subsequently an intramolecular normal Staudinger/aza-Wittig reaction to form the quinolone ring in satisfactory yields.
GRAPHICAL ABSTRACT
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SUPPLEMENTAL MATERIAL
Full experimental details, IR, CHN analysis, mass spectra, and 1H NMR and 13C NMR spectra for this article can be accessed on the publisher’s website.