ABSTRACT
The chemistry of 1,2,5-triazepines and related compounds is reported. The investigated heterocycles are monocyclic and fused 1,2,5-triazepines. The different sections cover the synthesis and reactions of monocyclic and fused heterocycles incorporating 1,2,5-triazepine ring systems. This review also covers modifications of the 1,2,5-triazepines into many useful ring systems using a host of reagents and other multistep transformations. The biological evaluation of the target compounds is described, as well as the synthetic applications. The reaction mechanisms are discussed.
GRAPHICAL ABSTRACT
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