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Synthetic Communications
An International Journal for Rapid Communication of Synthetic Organic Chemistry
Volume 46, 2016 - Issue 8
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Original Articles

Practical synthesis of β-isothiocyanato ketones from chalcones

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Pages 678-684 | Received 24 Dec 2015, Published online: 04 May 2016
 

ABSTRACT

Practical synthesis of 1,3-diaryl-substituted 3-isothiocyanatopropan-1-ones based on the reaction of chalcones with thiocyanic acid generated in situ by treatment of thiocyanate ammonium with dilute sulfuric acid has been developed.

GRAPHICAL ABSTRACT

Acknowledgments

This research was financially supported by the Ministry of Education and Science of the Russian Federation (project part of government order, 4.1849.2014/K) and Russian Foundation for Basic Research (Grant No. 15-03-07564).

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