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Synthetic Communications
An International Journal for Rapid Communication of Synthetic Organic Chemistry
Volume 46, 2016 - Issue 8
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Original Articles

FeCl3-silica: A green approach for the synthesis of nitriles from oximes

, , &
Pages 685-691 | Received 07 Dec 2015, Published online: 04 May 2016
 

ABSTRACT

A green and suitable protocol for the conversion of aldoximes into nitriles is described. The transformation is carried out under solvent-free conditions using FeCl3-silica medium. The protocol offers a green, single-step facile procedure with the use of less toxic metal salt to isolate nitriles in good to excellent yields.

GRAPHICAL ABSTRACT

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