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ABSTRACT
This review covers many reports of the applications of multicomponent domino reactions (MDRs) in the synthesis of novel stereocontrolled mercapto-heterocycles from the 1972 up to the end of 2016. The reported approaches were employed for modifications of the oxathiolanone core for new construction of a mercapto-heterocycles scaffold from mercaptoacetyl transfer agent with various reagents.
GRAPHICAL ABSTRACT
Acknowledgment
The authors are indebted to Mansoura University for all support and the facilities provided.