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Synthetic Communications
An International Journal for Rapid Communication of Synthetic Organic Chemistry
Volume 48, 2018 - Issue 10
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SYNTHETIC COMMUNICATIONS REVIEWS

Current perspectives on quinazolines with potent biological activities: A review

Tanya GuptaDepartment of Pharmaceutical Chemistry, School of Pharmaceutical Education & Research, Jamia Hamdard, New Delhi, IndiaView further author information
,
Ankit RohillaDepartment of Pharmaceutical Chemistry, School of Pharmaceutical Education & Research, Jamia Hamdard, New Delhi, IndiaView further author information
,
Ankita PathakDepartment of Pharmaceutical Chemistry, School of Pharmaceutical Education & Research, Jamia Hamdard, New Delhi, IndiaView further author information
,
Md Jawaid AkhtarDepartment of Pharmaceutical Chemistry, School of Pharmaceutical Education & Research, Jamia Hamdard, New Delhi, IndiaView further author information
,
Md Rafi HaiderDepartment of Pharmaceutical Chemistry, School of Pharmaceutical Education & Research, Jamia Hamdard, New Delhi, IndiaView further author information
&
M. Shahar YarDepartment of Pharmaceutical Chemistry, School of Pharmaceutical Education & Research, Jamia Hamdard, New Delhi, IndiaCorrespondence[email protected]
ORCID Iconhttp://orcid.org/0000-0001-9298-0154View further author information
ORCID Icon
Pages 1099-1127 | Received 08 Dec 2017, Published online: 16 Mar 2018
 
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ABSTRACT

Quinazoline is a heterocyclic compound having biological activities. It is aromatic in nature having bicyclic structure containing benzene ring and pyrimidine ring. Quinazoline and its derivatives are found to have wide range of biological activities that is anticancer, analgesic, antimicrobial, antihypertensive, anticonvulsant, antimalarial, antitumor, and anti-tubercular activities. The purpose of this review is to highlight the recent researches made by researchers on various biological activities of quinazoline derivatives on different targets.

GRAPHICAL ABSTRACT

Additional information

Funding

This work was supported by the All India Council for Technical Education [Grant Number JH/FP/Pharm Chem/2017].

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