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Synthetic Communications
An International Journal for Rapid Communication of Synthetic Organic Chemistry
Volume 48, 2018 - Issue 9
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Original Articles

Catalyst-free benzylic C(sp3)-H functionalization of methyl quinolines with tryptanthrins

, , , &
Pages 1092-1098 | Received 21 Aug 2017, Published online: 09 Apr 2018
 

ABSTRACT

A simple and efficient method of catalyst free for the sp3 C–H bond activation of methyl aza-arene and nucleophilic addition to tryptanthrins in DMF was developed. Importantly, the more efficient and green isolation strategy of the purification of the products by centrifugation with 90% yields was applied.

GRAPHICAL ABSTRACT

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