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ABSTRACT
Molecular iodine has been used for the regioselective, one pot, direct synthesis of 3-iodoflavones from 2′-allyloxy chalcones, 2′-hydroxy chalcones and flavones. Allyl deprotection, cyclization dehydrogenation and α-iodination of 2′-allyloxychalcones has been achieved in a single step to offer 3-iodoflavones.
GRAPHICAL ABSTRACT
Acknowledgment
Avinash M. Patil and Dayanand A. Kamble thank CSIR, New Delhi and UGC-DSK for the award of research fellowships.
Additional information
Funding
This work was supported by the University Grants Commission, DSK, India [Grant Number F.4-2/2006 (BSR)/CH/15-16/0079] and Council for Scientific and Industrial Research, India [Grant Number 09/137(0534)/2012-EMR-I].